BDBM50000263 2-(3,4-Dichloro-phenyl)-1-(8-pyrrolidin-1-ylmethyl-1,4-dioxa-7-aza-spiro[4.5]dec-7-yl)-ethanone::CHEMBL358727

SMILES Clc1ccc(CC(=O)N2CC3(CC[C@H]2CN2CCCC2)OCCO3)cc1Cl

InChI Key InChIKey=NPBLSUKEFKYGMO-INIZCTEOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000263   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000263(2-(3,4-Dichloro-phenyl)-1-(8-pyrrolidin-1-ylmethyl...)
Affinity DataIC50:  160nMAssay Description:Opioid receptor kappa 1 agonist potency was determined in vitro using rabbit vas deferens (LVD) preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed