BDBM50000570 3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol::CHEMBL285250

SMILES CN1CCC2(CCCC1C2)c1cccc(O)c1

InChI Key InChIKey=ZQJGRSYDDMBMPJ-UHFFFAOYSA-N

Data  10 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50000570   

TargetMu-type opioid receptor(CALF)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataKi:  19nMAssay Description:Binding affinity of the compound towards opioid receptor mu 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards opioid receptor mu 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataKi:  78nMAssay Description:Binding affinity of the compound towards Opioid receptor kappa 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataKi:  98nMAssay Description:Binding affinity of the compound towards opioid receptor mu 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataKi:  160nMAssay Description:Binding affinity of the compound towards opioid receptor kappa 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataKi:  200nMAssay Description:Binding affinity of the compound towards opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataKi: >500nMAssay Description:Binding affinity of the compound towards Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataKi: >500nMAssay Description:Binding affinity of the compound towards opioid receptor mu 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataIC50:  21nMAssay Description:Inhibition of [3H]DAMGO radioligand binding to rat brain opioid receptor mu 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataIC50:  21nMAssay Description:Inhibition of [3H]DAMGO radioligand binding to rat brain opioid receptor mu 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]DADLE radioligand binding to rat brain opioid receptor delta 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataIC50:  911nMAssay Description:Inhibition of [3H]U-69593 radioligand binding to Guinea pig opioid receptor kappa 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]DADLE radioligand binding to rat brain opioid receptor delta 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataIC50:  557nMAssay Description:Opioid activity against delta-receptor of isolated mouse vas deferens(MVD) at 30 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000570(3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol |...)
Affinity DataIC50:  169nMAssay Description:The opioid activity against the mu-receptor in the isolated guinea pig ileum(GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed