BDBM50000935 7-(5-Oxo-5-piperidin-1-yl-pentyl)-1,3-dihydro-imidazo[4,5-b]quinolin-2-one::CHEMBL91204

SMILES O=C(CCCCc1ccc2nc3[nH]c(=O)[nH]c3cc2c1)N1CCCCC1

InChI Key InChIKey=IAUZGCNQOIQSCT-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000935   

TargetP2Y purinoceptor 12(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000935(7-(5-Oxo-5-piperidin-1-yl-pentyl)-1,3-dihydro-imid...)
Affinity DataEC50:  420nMAssay Description:Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000935(7-(5-Oxo-5-piperidin-1-yl-pentyl)-1,3-dihydro-imid...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human platelet PDE by inhibiting cyclic Adenosine monophosphate (cAMP) hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000935(7-(5-Oxo-5-piperidin-1-yl-pentyl)-1,3-dihydro-imid...)
Affinity DataEC50:  1.55E+4nMAssay Description:Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed