BDBM50000940 7-(5-Hydroxy-pentyl)-1,3-dihydro-imidazo[4,5-b]quinolin-2-one::CHEMBL328755

SMILES OCCCCCc1ccc2nc3[nH]c(=O)[nH]c3cc2c1

InChI Key InChIKey=YUYJVWMDBVJKPA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50000940   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000940(7-(5-Hydroxy-pentyl)-1,3-dihydro-imidazo[4,5-b]qui...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human platelet PDE by inhibiting cyclic Adenosine monophosphate (cAMP) hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000940(7-(5-Hydroxy-pentyl)-1,3-dihydro-imidazo[4,5-b]qui...)
Affinity DataEC50:  2.95E+3nMAssay Description:Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed