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BDBM50001641 6-(4,6-Diphenyl-pyridin-2-yloxy)-2-methyl-hexanoic acid::CHEMBL137581

SMILES: CC(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)C(O)=O

InChI Key: InChIKey=XIBSKSKOXONPOQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001641   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LTB4R


(HUMAN)
BDBM50001641
PNG
(6-(4,6-Diphenyl-pyridin-2-yloxy)-2-methyl-hexanoic...)
Show SMILES CC(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C24H25NO3/c1-18(24(26)27)10-8-9-15-28-23-17-21(19-11-4-2-5-12-19)16-22(25-23)20-13-6-3-7-14-20/h2-7,11-14,16-18H,8-10,15H2,1H3,(H,26,27)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50001641
PNG
(6-(4,6-Diphenyl-pyridin-2-yloxy)-2-methyl-hexanoic...)
Show SMILES CC(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C24H25NO3/c1-18(24(26)27)10-8-9-15-28-23-17-21(19-11-4-2-5-12-19)16-22(25-23)20-13-6-3-7-14-20/h2-7,11-14,16-18H,8-10,15H2,1H3,(H,26,27)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50001641
PNG
(6-(4,6-Diphenyl-pyridin-2-yloxy)-2-methyl-hexanoic...)
Show SMILES CC(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C24H25NO3/c1-18(24(26)27)10-8-9-15-28-23-17-21(19-11-4-2-5-12-19)16-22(25-23)20-13-6-3-7-14-20/h2-7,11-14,16-18H,8-10,15H2,1H3,(H,26,27)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Centre de Recherche de Vitry-Alfortville

Curated by ChEMBL


Assay Description
Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes


J Med Chem 35: 4315-24 (1992)


Article DOI: 10.1021/jm00101a008
BindingDB Entry DOI: 10.7270/Q2QR4W2W
More data for this
Ligand-Target Pair