BDBM50001645 6-[6-(2-Fluoro-phenyl)-4-phenyl-pyridin-2-yloxy]-2-methyl-hexanoic acid::CHEMBL344230

SMILES CC(CCCCOc1cc(cc(n1)-c1ccccc1F)-c1ccccc1)C(O)=O

InChI Key InChIKey=XHRNNMAQJJKUCE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001645   

TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001645(6-[6-(2-Fluoro-phenyl)-4-phenyl-pyridin-2-yloxy]-2...)
Affinity DataIC50:  70nMAssay Description:Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001645(6-[6-(2-Fluoro-phenyl)-4-phenyl-pyridin-2-yloxy]-2...)
Affinity DataIC50:  18nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001645(6-[6-(2-Fluoro-phenyl)-4-phenyl-pyridin-2-yloxy]-2...)
Affinity DataIC50:  4nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed