BindingDB BDBM50001733 CHEMBL3133821

BDBM50001733 CHEMBL3133821

SMILES Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1

InChI Key InChIKey=RXPZOSHFGJWSLQ-UHFFFAOYSA-N

Data 30 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50001733

Serine/threonine-protein kinase pim-2(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human PIM2More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Tyrosine-protein kinase JAK3(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human JAK3More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Serine/threonine-protein kinase Nek2(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human NEK2More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Calcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human CAMK4More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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MAP kinase-activated protein kinase 3(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human MAPKAPK3More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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MAP kinase-activated protein kinase 5(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human MAPKAPK5More data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Serine/threonine-protein kinase MARK1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human MARK1More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

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ALK tyrosine kinase receptor(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: 2.20E+3nMAssay Description:Inhibition of human ALK1More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
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Proto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: 3.04E+3nMAssay Description:Inhibition of human SrcMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Protein-tyrosine kinase 6(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: 3.20nMAssay Description:Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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MAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human MARK3More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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RAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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RAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Myotonin-protein kinase(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human DMPKMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Serine/threonine-protein kinase VRK1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human VRK1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Serine/threonine-protein kinase 24(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human MST3More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Serine/threonine-protein kinase 26(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human MST4More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Serine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human PAK1More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Serine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human PAK2More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Serine/threonine-protein kinase PAK 3(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human PAK3More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Mitogen-activated protein kinase 3(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human ERK1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Mitogen-activated protein kinase 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human ERK2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mitogen-activated protein kinase 8(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human JNK1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mitogen-activated protein kinase 10(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human JNK3More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Homeodomain-interacting protein kinase 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human HIPK1More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Homeodomain-interacting protein kinase 2(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human HIPK2More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Homeodomain-interacting protein kinase 3(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human HIPK3More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Serine/threonine-protein kinase Nek1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

BDBM50001733(CHEMBL3133821)

IC50: >1.00E+4nMAssay Description:Inhibition of human NEK1More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Filter my 30 hits

Targets 30▿
- Mitogen-activated protein kinase 1 1
- Mitogen-activated protein kinase 3 1
- Myotonin-protein kinase 1
- Serine/threonine-protein kinase pim-2 1
- Mitogen-activated protein kinase 8 1
- Calcium/calmodulin-dependent protein kinase type IV 1
- Homeodomain-interacting protein kinase 2 1
- Homeodomain-interacting protein kinase 1 1
- Protein-tyrosine kinase 6 1
- ALK tyrosine kinase receptor 1
- Glycogen synthase kinase-3 beta 1
- Serine/threonine-protein kinase VRK1 1
- Serine/threonine-protein kinase Nek2 1
- RAC-gamma serine/threonine-protein kinase 1
- Serine/threonine-protein kinase Nek1 1
- Mitogen-activated protein kinase 10 1
- RAC-beta serine/threonine-protein kinase 1
- MAP/microtubule affinity-regulating kinase 3 1
- Serine/threonine-protein kinase 26 1
- Serine/threonine-protein kinase PAK 1 1
- Homeodomain-interacting protein kinase 3 1
- Serine/threonine-protein kinase 24 1
- Serine/threonine-protein kinase PAK 2 1
- RAC-alpha serine/threonine-protein kinase 1
- Serine/threonine-protein kinase PAK 3 1
- Serine/threonine-protein kinase MARK1 1
- Tyrosine-protein kinase JAK3 1
- MAP kinase-activated protein kinase 3 1
- Proto-oncogene tyrosine-protein kinase Src 1
- MAP kinase-activated protein kinase 5 1
Publications 1▿
- Bioorg Med Chem Lett 24: 1948-51 (2014) 30
Institutions 1▿
- Martin-Luther-University Halle-Wittenberg 30
Affinity: 3.2 to 1.0E+4 nM▿
- IC50 30
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 1