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BDBM50002096 ALO-4943A::CHEMBL1719::KW-4679::OLOPATADINE HYDROCHLORIDE::Olopatadine::Pataday::Patanol::[11-(3-Dimethylamino-propylidene)-6,11-dihydro-dibenzo[b,e]oxepin-2-yl]-acetic acid; hydrochloride

SMILES: CN(C)CC\C=C1\c2ccccc2COc2ccc(CC(O)=O)cc12

InChI Key: InChIKey=JBIMVDZLSHOPLA-LSCVHKIXSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002096   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50002096
PNG
(ALO-4943A | CHEMBL1719 | KW-4679 | OLOPATADINE HYD...)
Show SMILES CN(C)CC\C=C1\c2ccccc2COc2ccc(CC(O)=O)cc12
Show InChI InChI=1S/C21H23NO3/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24)/b18-8-
UniProtKB/SwissProt

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Similars

PubMed
16n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity for histamine H1 receptor from guinea pig cerebellum, using [3H]pyrilamine as radioligand at 0.1 uM


J Med Chem 35: 2074-84 (1992)

More data for this
Ligand-Target Pair