BDBM50002310 3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydrobromide::CHEMBL1188090::CHEMBL545783

SMILES CCCN(CCc1ccccc1)CCc1cccc(O)c1

InChI Key InChIKey=QUZUPTMNMJTYGL-UHFFFAOYSA-N

Data  6 KI  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50002310   

TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]YM-09151-2 from human dopamine D3 receptor expressed in CHOp cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]YM-09151-2 from human dopamine D2 receptor expressed in CHOp cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataKi:  594nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataKi:  3.71E+3nMAssay Description:Displacement of [3H]pCl-DPDPE from human delta opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in LHD1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataIC50:  57nMAssay Description:Displacement of [3H]ethylketocyclazocine from kappa opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataIC50:  750nMAssay Description:Inhibitory activity against [3H]spiperone in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataEC50:  39nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as stimulation of mitogenesis incubated for 24 hrs by [3H]thymidine i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataEC50:  5.30nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as stimulation of mitogenesis incubated for 24 hrs by [3H]thymidine i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataIC50:  9.28E+4nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed