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BDBM50003271 3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-(3-methyl-thiophen-2-ylmethyl)-acrylic acid::CHEMBL124859

SMILES: CCCCc1ncc(\C=C(/Cc2sccc2C)C(O)=O)n1Cc1ccccc1Cl

InChI Key: InChIKey=MLWFVZZPDTYBOO-LDADJPATSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003271   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II AT1B


(RAT)
BDBM50003271
PNG
(3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2...)
Show SMILES CCCCc1ncc(\C=C(/Cc2sccc2C)C(O)=O)n1Cc1ccccc1Cl
Show InChI InChI=1S/C23H25ClN2O2S/c1-3-4-9-22-25-14-19(26(22)15-17-7-5-6-8-20(17)24)12-18(23(27)28)13-21-16(2)10-11-29-21/h5-8,10-12,14H,3-4,9,13,15H2,1-2H3,(H,27,28)/b18-12+
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Similars

Article
PubMed
n/an/a 730n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Angiotensin II receptor specific binding to rat mesenteric arteries


J Med Chem 35: 3858-72 (1992)


Article DOI: 10.1021/jm00099a013
BindingDB Entry DOI: 10.7270/Q23T9G4T
More data for this
Ligand-Target Pair