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BDBM50005072 5,7-Dichloro-4-(3-p-tolyl-ureido)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL61153

SMILES: Cc1ccc(NC(=O)N[C@H]2C[C@@H](Nc3cc(Cl)cc(Cl)c23)C(O)=O)cc1

InChI Key: InChIKey=SPFYQISIAZRTPO-LSDHHAIUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005072   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate-NMDA


(RAT)
BDBM50005072
PNG
(5,7-Dichloro-4-(3-p-tolyl-ureido)-1,2,3,4-tetrahyd...)
Show SMILES Cc1ccc(NC(=O)N[C@H]2C[C@@H](Nc3cc(Cl)cc(Cl)c23)C(O)=O)cc1
Show InChI InChI=1S/C18H17Cl2N3O3/c1-9-2-4-11(5-3-9)21-18(26)23-14-8-15(17(24)25)22-13-7-10(19)6-12(20)16(13)14/h2-7,14-15,22H,8H2,1H3,(H,24,25)(H2,21,23,26)/t14-,15+/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.


J Med Chem 35: 1954-68 (1992)


Article DOI: 10.1021/jm00089a004
BindingDB Entry DOI: 10.7270/Q2T72GCZ
More data for this
Ligand-Target Pair