BDBM50005247 (+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine::(-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine::(R)-(-)-2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine::(S)-(+)-2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine::2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine::2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine((R)-(-)-MDA)::3,4-methylenedioxyamphetamine::CHEMBL6731::MDA::MDA, (R,S)::MDA,R(-)::Tenamfetamine::methylenedioxyamphetamine

SMILES CC(N)Cc1ccc2OCOc2c1

InChI Key InChIKey=NGBBVGZWCFBOGO-UHFFFAOYSA-N

Data  19 KI  10 IC50  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50005247   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  100nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNorepinephrine transporter(RAT)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  108nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  117nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  160nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  190nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  190nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  387nMAssay Description:ability to displace [3H]- Mazindol binding to cocaine binding sites on Dopamine transporter of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  2.10E+3nMAssay Description:Compound was tested for binding affinity towards 5-HT1C (5-HT1C) receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  2.19E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]ketanserin as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  2.19E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]ketanserin as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  2.29E+3nMAssay Description:Compound was tested for binding affinity towards 5-HT1C (5-HT1C) receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  2.60E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  2.75E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi:  3.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Texas At Austin

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataEC50:  160nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataKd:  355nMAssay Description:Affinity against 5-hydroxytryptamine 2B receptor in the isolated rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Texas At Austin

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  900nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  890nMAssay Description:Binding affinity to human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  266nMAssay Description:Binding affinity to human NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Texas At Austin

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  478nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  890nMAssay Description:Inhibition of human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  266nMAssay Description:Inhibition of human noradrenaline transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  478nMAssay Description:Inhibition of [3H]5-HT uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  996nMAssay Description:Inhibition of [3H]5-HT reuptake at rat SERT expressed in HEK293 cells after 2 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  478nMAssay Description:Activity towards Serotonin transporter was determined by the ability to inhibit [3H]-5-HT uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataEC50:  190nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  266nMAssay Description:Compound was tested for the ability to inhibit [3H]-norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed