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BDBM50006087 3-(3-{[3-(4-Benzyloxy-phenoxy)-2-methoxy-propoxy]-hydroxy-phosphoryloxy}-benzyl)-thiazol-3-ium::CHEMBL42725

SMILES: COC(COc1ccc(OCc2ccccc2)cc1)COP([O-])(=O)Oc1cccc(C[n+]2ccsc2)c1

InChI Key: InChIKey=XTWUPRZWRBKTAB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006087   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50006087
PNG
(3-(3-{[3-(4-Benzyloxy-phenoxy)-2-methoxy-propoxy]-...)
Show SMILES COC(COc1ccc(OCc2ccccc2)cc1)COP([O-])(=O)Oc1cccc(C[n+]2ccsc2)c1
Show InChI InChI=1S/C27H28NO7PS/c1-31-27(19-33-25-12-10-24(11-13-25)32-18-22-6-3-2-4-7-22)20-34-36(29,30)35-26-9-5-8-23(16-26)17-28-14-15-37-21-28/h2-16,21,27H,17-20H2,1H3
MMDB

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Similars

Article
PubMed
n/an/a 1.49E+4n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
Inhibition of PAF induced platelet aggregation in rabbit


J Med Chem 35: 1650-62 (1992)


Article DOI: 10.1021/jm00087a023
BindingDB Entry DOI: 10.7270/Q2BC4058
More data for this
Ligand-Target Pair