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BDBM50006959 4-[2-(1,3-Dioxo-1,3,4,9-tetrahydro-2,4,9-triaza-fluoren-2-yl)-ethyl]-piperazine-1-carboxylic acid ethyl ester::CHEMBL55456

SMILES: CCOC(=O)N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1

InChI Key: InChIKey=ZIHPQZZASJCSAD-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006959   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006959
PNG
(4-[2-(1,3-Dioxo-1,3,4,9-tetrahydro-2,4,9-triaza-fl...)
Show SMILES CCOC(=O)N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1
Show InChI InChI=1S/C19H23N5O4/c1-2-28-19(27)23-10-7-22(8-11-23)9-12-24-17(25)16-15(21-18(24)26)13-5-3-4-6-14(13)20-16/h3-6,20H,2,7-12H2,1H3,(H,21,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity measured for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair