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BDBM50006962 2-(2-Piperazin-1-yl-ethyl)-4,9-dihydro-2,4,9-triaza-fluorene-1,3-dione::CHEMBL57398

SMILES: O=c1[nH]c2c3ccccc3[nH]c2c(=O)n1CCN1CCNCC1

InChI Key: InChIKey=VOIMSYYRDZIFTE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006962   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006962
PNG
(2-(2-Piperazin-1-yl-ethyl)-4,9-dihydro-2,4,9-triaz...)
Show SMILES O=c1[nH]c2c3ccccc3[nH]c2c(=O)n1CCN1CCNCC1
Show InChI InChI=1S/C16H19N5O2/c22-15-14-13(11-3-1-2-4-12(11)18-14)19-16(23)21(15)10-9-20-7-5-17-6-8-20/h1-4,17-18H,5-10H2,(H,19,23)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for Alpha-1 adrenergic receptor measured by displacing [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair