BDBM50007303 6-(4'-Fluoro-3,5-diisopropyl-biphenyl-2-yloxymethyl)-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL318707

SMILES CC(C)c1cc(C(C)C)c(OCC2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(F)cc1

InChI Key InChIKey=JMEOINPEUMGNEF-FIWHBWSRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007303   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007303(6-(4'-Fluoro-3,5-diisopropyl-biphenyl-2-yloxymethy...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed