BDBM50007517 (S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-5,6-dimethoxybenzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-5,6-dimethoxy-benzamide::CHEMBL76402

SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(OC)c1OC

InChI Key InChIKey=WGLPSCZHULDZSS-JTQLQIEISA-N

Data  6 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50007517   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre

Curated by ChEMBL
LigandPNGBDBM50007517((S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-h...)
Affinity DataKi:  0.0640nMAssay Description:Inhibition of [3H]raclopride binding to rat striatal dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre

Curated by ChEMBL
LigandPNGBDBM50007517((S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-h...)
Affinity DataKi:  0.0640nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50007517((S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-h...)
Affinity DataKi:  0.420nMAssay Description:Displacement of [3H]spiperone from dopamine D3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50007517((S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-h...)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]spiperone from dopamine D2long receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50007517((S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-h...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]spiperone from dopamine D2short receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50007517((S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-h...)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of [3H]SCH23990 from dopamine D1 receptor in pig stratial membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre

Curated by ChEMBL
LigandPNGBDBM50007517((S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-h...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal dopamine receptor D2 was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre

Curated by ChEMBL
LigandPNGBDBM50007517((S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-h...)
Affinity DataIC50:  1.40nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Astra Research Centre

Curated by ChEMBL
LigandPNGBDBM50007517((S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-h...)
Affinity DataIC50:  1.40nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed