BDBM50008131 2-[2-(4-Methyl-piperazine-1-sulfonylamino)-3-phenyl-propionylamino]-pent-4-enoic acid [1-cyclohexylmethyl-3,3-difluoro-3-(2-morpholin-4-yl-ethylcarbamoyl)-2-oxo-propyl]-amide; Hydrate::CHEMBL31268

SMILES CN1CCN(CC1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC=C)C(=O)N[C@@H](CC1CCCCC1)C(=O)C(F)(F)C(=O)NCCN1CCOCC1

InChI Key InChIKey=YIJIVLJRFZJKEV-CHQNGUEUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008131   

TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008131(2-[2-(4-Methyl-piperazine-1-sulfonylamino)-3-pheny...)
Affinity DataIC50:  728nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008131(2-[2-(4-Methyl-piperazine-1-sulfonylamino)-3-pheny...)
Affinity DataIC50:  0.920nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed