BDBM50008444 CHEMBL140750::{4-Oxo-3-[(3-trifluoromethyl-phenylthiocarbamoyl)-methyl]-3,4-dihydro-phthalazin-1-yl}-acetic acid

SMILES OC(=O)Cc1nn(CC(=S)Nc2cccc(c2)C(F)(F)F)c(=O)c2ccccc12

InChI Key InChIKey=BQGZHCKZMCYAKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008444   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50008444(CHEMBL140750 | {4-Oxo-3-[(3-trifluoromethyl-phenyl...)
Affinity DataIC50:  52nMAssay Description:In vitro inhibitory activity against aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed