BDBM50008996 2-Thiazol-5-ylmethyl-1,2-dihydro-indazol-3-one::CHEMBL3144715

SMILES O=c1n(Cc2cncs2)[nH]c2ccccc12

InChI Key InChIKey=KPXSUQVYEHMEMW-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008996   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008996(2-Thiazol-5-ylmethyl-1,2-dihydro-indazol-3-one | C...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008996(2-Thiazol-5-ylmethyl-1,2-dihydro-indazol-3-one | C...)
Affinity DataEC50:  2.16E+4nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008996(2-Thiazol-5-ylmethyl-1,2-dihydro-indazol-3-one | C...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed