BDBM50009094 CHEMBL3237993

SMILES CNS(=O)(=O)c1ccc(cc1)N1CCN(C[C@@H]1C#CC)S(=O)(=O)c1ccc(N)nc1

InChI Key InChIKey=AZCZVIWSFGSHOZ-INIZCTEOSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009094   

TargetGlucokinase regulatory protein(Mus musculus)
Amgen

Curated by ChEMBL

LigandBDBM50009094(CHEMBL3237993)Copy SMILESCopy InChI

Affinity DataEC50:  97nMAssay Description:Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50009094(CHEMBL3237993)Copy SMILESCopy InChI

Affinity DataIC50:  35nMAssay Description:Inhibition of biotin-tagged human GKRP/fluorescein-tagged GK interaction preincubated for 20 mins prior to GK addition measured after 2 to 4 hrs by A...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI