BDBM50009576 CHEMBL3234447

SMILES CCN(CC)c1ccc2c(-c3ccc(cc3S([O-])(=O)=O)S(=O)(=O)NCCCCCCCCCCCCNC(=O)NCCCC[C@H](NC(=O)Cc3csc(=[NH2+])n3C)C(=O)N[C@@H](Cc3cn(Cc4ccccc4)c[n+]3C)C(=O)NC3CC[NH+](C)CC3)c3ccc(cc3oc2c1)=[N+](CC)CC

InChI Key InChIKey=KUDFPXVGQHWSJN-NTGUUYCISA-Q

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009576   

TargetApelin(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50009576(CHEMBL3234447)
Affinity DataKi:  690nMAssay Description:Displacement of [125I]-pE13F from human apelin receptor expressed in CHO cell membranes after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50009576(CHEMBL3234447)
Affinity DataKi:  2.23E+3nMAssay Description:Displacement of [125I]-angiotensin 2 from human angiotensin 2 type-1 receptor expressed in CHO cell membranes after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin(Rattus norvegicus)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50009576(CHEMBL3234447)
Affinity DataIC50:  4.30E+3nMAssay Description:Agonist activity at rat apelin receptor expressed in CHO cell membranes coexpressing EGFP assessed as inhibition of forskolin-induced cAMP production...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed