BDBM50009847 CHEMBL428672::ethyl 6-fluoro-4',5'-dioxospiro[3,4-dihydro-2H-chromene-4,2'-(tetrahydro-1'H-pyrrole)]-3'-carboxylate

SMILES CCOC(=O)C1C(=O)C(=O)NC11CCOc2ccc(F)cc12

InChI Key InChIKey=XVQHCPUZEQPNIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009847   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009847(CHEMBL428672 | ethyl 6-fluoro-4',5'-dioxospiro[3,4...)
Affinity DataIC50:  910nMAssay Description:Inhibitory activity measured against rat lens aldose reductase using 3-pyridinecarboxaldehyde as substrateChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed