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BDBM50010101 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate::Bentyl::Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester::CHEMBL1123::DICYCLOMINE::Dicycloverin

SMILES: CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1

InChI Key: InChIKey=CURUTKGFNZGFSE-UHFFFAOYSA-N

Data: 9 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50010101   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50010101
PNG
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)
Show SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
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PubMed
0.620n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Mol Pharmacol 38: 805-15 (1990)

More data for this
Ligand-Target Pair
CHRM4


(RABBIT)
BDBM50010101
PNG
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)
Show SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
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PubMed
1.51n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Mol Pharmacol 38: 805-15 (1990)

More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50010101
PNG
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)
Show SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
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PubMed
1.78n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Mol Pharmacol 38: 805-15 (1990)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50010101
PNG
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)
Show SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
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PubMed
2.5n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Displacement of [3H]pirenzepine from muscarinic acetylcholine receptor M1 in rat cortex homogenates


J Med Chem 34: 2984-9 (1991)

More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50010101
PNG
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)
Show SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
PDB

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PubMed
5.10n/an/an/an/an/an/an/an/a



National Institute of Mental Health

Curated by PDSP Ki Database




Mol Pharmacol 35: 469-76 (1989)

More data for this
Ligand-Target Pair
CHRM4


(Chick)
BDBM50010101
PNG
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)
Show SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
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PubMed
5.5n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Mol Pharmacol 38: 805-15 (1990)

More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50010101
PNG
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)
Show SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
PDB

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PubMed
32.4n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Mol Pharmacol 38: 805-15 (1990)

More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50010101
PNG
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)
Show SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
PDB

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PubMed
47n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Displacement of [3H](-)-quinuclidinyl benzilate(QNB) from muscarinic (M2) receptor in rat heart homogenates


J Med Chem 34: 2984-9 (1991)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50010101
PNG
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)
Show SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
UniProtKB/SwissProt

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PubMed
244n/an/an/an/an/an/an/an/a



National Institute of Mental Health

Curated by PDSP Ki Database




Mol Pharmacol 35: 469-76 (1989)

More data for this
Ligand-Target Pair