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BDBM50010151 6-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylmethyl)-2-methyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid::CHEMBL107271

SMILES: CCCCc1nc(Cl)c(CO)n1Cc1ccc2CC(C)(CCc2c1)C(O)=O

InChI Key: InChIKey=MIKKFRRWKWWJCI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010151   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II AT1B


(RAT)
BDBM50010151
PNG
(6-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylm...)
Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc2CC(C)(CCc2c1)C(O)=O
Show InChI InChI=1S/C21H27ClN2O3/c1-3-4-5-18-23-19(22)17(13-25)24(18)12-14-6-7-16-11-21(2,20(26)27)9-8-15(16)10-14/h6-7,10,25H,3-5,8-9,11-13H2,1-2H3,(H,26,27)
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Similars

Article
PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



Ciba Geigy Limited

Curated by ChEMBL


Assay Description
Binding affinity against angiotensin II receptor in rat smooth muscle cell preparations


J Med Chem 34: 3105-14 (1991)


Article DOI: 10.1021/jm00114a021
BindingDB Entry DOI: 10.7270/Q27S7MRP
More data for this
Ligand-Target Pair