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BDBM50010154 6-(2-Butyl-5-chloro-4-hydroxymethyl-imidazol-1-ylmethyl)-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid::CHEMBL104684

SMILES: CCCCc1nc(CO)c(Cl)n1Cc1ccc2CC(CCc2c1)C(O)=O

InChI Key: InChIKey=UBSQOYFUKVUCDC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010154   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II AT1B


(RAT)
BDBM50010154
PNG
(6-(2-Butyl-5-chloro-4-hydroxymethyl-imidazol-1-ylm...)
Show SMILES CCCCc1nc(CO)c(Cl)n1Cc1ccc2CC(CCc2c1)C(O)=O
Show InChI InChI=1S/C20H25ClN2O3/c1-2-3-4-18-22-17(12-24)19(21)23(18)11-13-5-6-15-10-16(20(25)26)8-7-14(15)9-13/h5-6,9,16,24H,2-4,7-8,10-12H2,1H3,(H,25,26)
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PC sid
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Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Ciba Geigy Limited

Curated by ChEMBL


Assay Description
Binding affinity against angiotensin II receptor in rat smooth muscle cell preparations


J Med Chem 34: 3105-14 (1991)


Article DOI: 10.1021/jm00114a021
BindingDB Entry DOI: 10.7270/Q27S7MRP
More data for this
Ligand-Target Pair