BDBM50010276 2-Fluorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-one 1',1'-Dioxide::CHEMBL324907

SMILES Fc1ccc2-c3ccccc3C3(CC(=O)NS3(=O)=O)c2c1

InChI Key InChIKey=PHSPODFTWJRKAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010276   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50010276(2-Fluorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-...)
Affinity DataIC50:  151nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase (L-HDH) from rat kidney (RK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50010276(2-Fluorospiro[9H-fluorene-9,5'-isothiazolidin]-3'-...)
Affinity DataIC50:  169nMAssay Description:In vitro inhibition of Aldose reductase (AR) from rat lens (RL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed