BDBM50010336 CHEMBL3263579

SMILES O=C(N1CCCCC1)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1

InChI Key InChIKey=SGQNTNACVSWXMA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50010336   

TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010336(CHEMBL3263579)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010336(CHEMBL3263579)
Affinity DataIC50:  0.200nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010336(CHEMBL3263579)
Affinity DataIC50:  0.210nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50010336(CHEMBL3263579)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed