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BDBM50010380 CHEMBL3263626

SMILES: NC(C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)CC1CCCCC1

InChI Key: InChIKey=MKVRCQVBVNSXAB-JJPFLPBXSA-N

Data: 3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010380   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone-lysine N-methyltransferase EHMT1


(Homo sapiens)
BDBM50010380
PNG
(CHEMBL3263626)
Show SMILES NC(C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)CC1CCCCC1
Show InChI InChI=1S/C18H28N6O3/c19-11(6-10-4-2-1-3-5-10)7-12-14(25)15(26)18(27-12)24-9-23-13-16(20)21-8-22-17(13)24/h8-12,14-15,18,25-26H,1-7,19H2,(H2,20,21,22)/t11?,12-,14-,15-,18-/m1/s1
PDB
MMDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of methyltransferase activity of EHMT1 (unknown origin)-mediated dimethylation of a biotinylated histone H3 peptide at lysine-9 by FRET-ba...


Citation and Details

Article DOI: 10.1021/ml4002503
BindingDB Entry DOI: 10.7270/Q2N58NWS
More data for this
Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 1 (DNMT1)


(Homo sapiens (Human))
BDBM50010380
PNG
(CHEMBL3263626)
Show SMILES NC(C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)CC1CCCCC1
Show InChI InChI=1S/C18H28N6O3/c19-11(6-10-4-2-1-3-5-10)7-12-14(25)15(26)18(27-12)24-9-23-13-16(20)21-8-22-17(13)24/h8-12,14-15,18,25-26H,1-7,19H2,(H2,20,21,22)/t11?,12-,14-,15-,18-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.79E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of DNMT1 (unknown origin)


Citation and Details

Article DOI: 10.1021/ml4002503
BindingDB Entry DOI: 10.7270/Q2N58NWS
More data for this
Ligand-Target Pair
Protein G9a (G9a)


(Homo sapiens (Human))
BDBM50010380
PNG
(CHEMBL3263626)
Show SMILES NC(C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)CC1CCCCC1
Show InChI InChI=1S/C18H28N6O3/c19-11(6-10-4-2-1-3-5-10)7-12-14(25)15(26)18(27-12)24-9-23-13-16(20)21-8-22-17(13)24/h8-12,14-15,18,25-26H,1-7,19H2,(H2,20,21,22)/t11?,12-,14-,15-,18-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of methyltransferase activity of EHMT2 (unknown origin)-mediated dimethylation of a biotinylated histone H3 peptide at lysine-9 by FRET-ba...


Citation and Details

Article DOI: 10.1021/ml4002503
BindingDB Entry DOI: 10.7270/Q2N58NWS
More data for this
Ligand-Target Pair