BDBM50010860 1-(1-(2-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol::1-[1-(2-Chloro-phenyl)-2-dimethylamino-ethyl]-cyclohexanol(HCl)::CHEMBL316862
SMILES CN(C)CC(c1ccccc1Cl)C1(O)CCCCC1
InChI Key InChIKey=OVSAXOVRTVDPOU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50010860
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataKi: 125nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 523nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of 5HT uptake at rat brain SERTMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of norepinephrine uptake at rat brain norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 205nMAssay Description:Inhibition of norepinephrine uptake at human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 177nMAssay Description:Inhibition of 5HT uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair