BDBM50011242 CHEMBL3260339

SMILES COC(=O)Nc1ccc-2c(NC(=O)[C@H](C)CCC[C@H](N3CCC(=CC3=O)c3c(Br)ccc(Cl)c3F)c3cc-2ccn3)c1

InChI Key InChIKey=NFRBICAIEMTSJZ-QUGAMOGWSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011242   

TargetCoagulation factor XI(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011242(CHEMBL3260339)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of human coagulation factor 11a after 20 to 180 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011242(CHEMBL3260339)
Affinity DataKi:  3nMAssay Description:Inhibition of human plasma kallikrein using S-2302 as substrate at 25 degC after 20 to 180 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed