BDBM50011421 2-(4-Nitro-phenyl)-chromen-4-one::CHEMBL64780

SMILES [O-][N+](=O)c1ccc(cc1)-c1cc(=O)c2ccccc2o1

InChI Key InChIKey=CKSVYVHLZNMXLX-UHFFFAOYSA-N

Data  2 KI  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50011421   

TargetAmine oxidase [flavin-containing] B(Human)
Birla Institute of Technology

LigandPNGBDBM50011421(2-(4-Nitro-phenyl)-chromen-4-one | CHEMBL64780)
Affinity DataKi:  200nMAssay Description:The activities of recombinant hMAO-A and hMAO-B were determined using p-tyramine as common substrate and calculated as 0.18 +/- 0.01 nmol/mg/min (n =...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Human)
Birla Institute of Technology

LigandPNGBDBM50011421(2-(4-Nitro-phenyl)-chromen-4-one | CHEMBL64780)
Affinity DataKi:  840nMAssay Description:The activities of recombinant hMAO-A and hMAO-B were determined using p-tyramine as common substrate and calculated as 0.18 +/- 0.01 nmol/mg/min (n =...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50011421(2-(4-Nitro-phenyl)-chromen-4-one | CHEMBL64780)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human full length ARTD1 using NAD+ as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50011421(2-(4-Nitro-phenyl)-chromen-4-one | CHEMBL64780)
Affinity DataIC50:  8.32E+3nMAssay Description:Inhibition of human full length ARTD2 using NAD+ as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50011421(2-(4-Nitro-phenyl)-chromen-4-one | CHEMBL64780)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of human full length ARTD1 using NAD+ as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Prin. K.M. Kundnani College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50011421(2-(4-Nitro-phenyl)-chromen-4-one | CHEMBL64780)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of Influenza A virus (H1N1) neuraminidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50011421(2-(4-Nitro-phenyl)-chromen-4-one | CHEMBL64780)
Affinity DataIC50: >2.00E+6nMAssay Description:Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50011421(2-(4-Nitro-phenyl)-chromen-4-one | CHEMBL64780)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of human full length ARTD2 using NAD+ as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed