BDBM50011503 CHEMBL3261927

SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(C[C@H](NC(=O)C2(N)CCOCC2)C#N)cc1

InChI Key InChIKey=VUCFAFRVHRIURK-IBGZPJMESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011503   

TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50011503(CHEMBL3261927)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of cathepsin C in human THP1 cells assessed as inhibition of H-Gly-Phe-AFC cleavage by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50011503(CHEMBL3261927)
Affinity DataIC50:  0.794nMAssay Description:Inhibition of recombinant human cathepsin C using H-Gly-Arg-AMC as substrate preincubated for 30 mins before substrate addition measured after 60 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50011503(CHEMBL3261927)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed