BDBM50011756 1-(4-Amino-phenyl)-3-cyclohexyl-3-aza-bicyclo[3.1.1]heptane-2,4-dione::CHEMBL27467

SMILES Nc1ccc(cc1)C12CC(C1)C(=O)N(C1CCCCC1)C2=O

InChI Key InChIKey=QQMGXUVJMQNZGE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50011756   

TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011756(1-(4-Amino-phenyl)-3-cyclohexyl-3-aza-bicyclo[3.1....)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011756(1-(4-Amino-phenyl)-3-cyclohexyl-3-aza-bicyclo[3.1....)
Affinity DataIC50:  1.40E+5nMAssay Description:In vitro inhibition of aldosterone production in rat adrenal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011756(1-(4-Amino-phenyl)-3-cyclohexyl-3-aza-bicyclo[3.1....)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50011756(1-(4-Amino-phenyl)-3-cyclohexyl-3-aza-bicyclo[3.1....)
Affinity DataIC50:  1.40E+5nMAssay Description:In vitro inhibition of progesterone production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed