BDBM50011888 5-(Carboxymethyl-amino)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanoic acid::CHEMBL32691

SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)NC(CCCNCC(O)=O)C(O)=O

InChI Key InChIKey=QCAVWVAVLRJWMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011888   

TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011888(5-(Carboxymethyl-amino)-2-{4-[(2,4-diamino-pteridi...)
Affinity DataIC50:  50nMAssay Description:Inhibition of dihydrofolate reductase(DHFR) enzyme from human leukemic lymphoblasts.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed