BDBM50011931 (2E)‐3‐phenylprop‐2‐en‐1‐yl(2E)‐2‐cyano‐3‐(3,4‐ dihydroxyphenyl)prop‐2‐enoate (C4)::2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-phenyl-allyl ester::CHEMBL37141

SMILES Oc1ccc(\C=C(/C#N)C(=O)OC\C=C\c2ccccc2)cc1O

InChI Key InChIKey=XGHYFEJMJXGPGN-UYHGDYIZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50011931   

TargetCaspase-1(Homo sapiens (Human))
Depaul University

LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)
Affinity DataIC50:  2.23E+3nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 µL total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)
Affinity DataIC50:  63nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)
Affinity DataIC50:  3.33E+3nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed