BDBM50012169 CHEMBL3264473

SMILES O=C([C@H]1COc2cc(Oc3ccccc3)ccc2C1)c1ncc(o1)-c1ccccn1

InChI Key InChIKey=KTRKLISDHZZCIZ-QGZVFWFLSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50012169   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012169(CHEMBL3264473)
Affinity DataKi:  18nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli using [14C]oleamide as substrate assessed as oleic acid formation by Dixon plot anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012169(CHEMBL3264473)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse brain ABHD6 incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012169(CHEMBL3264473)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse brain MAGL incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012169(CHEMBL3264473)
Affinity DataIC50:  90nMAssay Description:Inhibition of mouse brain FAAH incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral cholesterol ester hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012169(CHEMBL3264473)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse brain KIAA1363 incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed