BDBM50013224 CHEMBL351355::Pyrrolidin-3-yl-acetic acid::Pyrrolidin-3-yl-acetic acid ((R)-(-)-Homo beta Proline)::Pyrrolidin-3-yl-acetic acid ((RS)-Homo beta Proline)

SMILES OC(=O)CC1CCNC1

InChI Key InChIKey=OUENRUZPZZFMCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013224   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50013224(CHEMBL351355 | Pyrrolidin-3-yl-acetic acid | Pyrro...)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50013224(CHEMBL351355 | Pyrrolidin-3-yl-acetic acid | Pyrro...)
Affinity DataIC50:  1.41E+4nMpH: 7.4Assay Description:In vitro binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptic membranes at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed