BDBM50014205 2-Hydroxy-5-methylsulfanyl-6-oxo-6-phenyl-hexa-2,4-dienoic acid ethyl ester::CHEMBL329606

SMILES CCOC(=O)C(=O)CC=C(SC)C(=O)c1ccccc1

InChI Key InChIKey=WYDPKZWJVRYMEM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014205   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre De Recherches De Vitry

Curated by ChEMBL
LigandPNGBDBM50014205(2-Hydroxy-5-methylsulfanyl-6-oxo-6-phenyl-hexa-2,4...)
Affinity DataIC50:  2.50E+3nMAssay Description:Iin vitro inhibition of 5-lipoxygenase activity in rat basophil leukemia type 1(RBL1) cell homogenates, (reduction of [14C]-5-HETE formation)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre De Recherches De Vitry

Curated by ChEMBL
LigandPNGBDBM50014205(2-Hydroxy-5-methylsulfanyl-6-oxo-6-phenyl-hexa-2,4...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibitory activity against 5-Lipoxygenase in rat by Peritoneal 5-lipoxygenase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Centre De Recherches De Vitry

Curated by ChEMBL
LigandPNGBDBM50014205(2-Hydroxy-5-methylsulfanyl-6-oxo-6-phenyl-hexa-2,4...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of 5-lipoxygenase in rat (peritoneal assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed