BDBM50015181 CHEMBL154302::N-Hydroxy-4-methyl-benzamide

SMILES Cc1ccc(cc1)C(=O)NO

InChI Key InChIKey=SFSSMGSFESHVQM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50015181   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50015181(CHEMBL154302 | N-Hydroxy-4-methyl-benzamide)
Affinity DataIC50:  6.50E+4nMAssay Description:In vitro inhibitory activity against RBL-1 5-LOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50015181(CHEMBL154302 | N-Hydroxy-4-methyl-benzamide)
Affinity DataIC50:  6.46E+4nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Italfarmaco

Curated by ChEMBL
LigandPNGBDBM50015181(CHEMBL154302 | N-Hydroxy-4-methyl-benzamide)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in Sf9 insect cells using Fluor de Lys deacetylase or Fluor de Lys ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Italfarmaco

Curated by ChEMBL
LigandPNGBDBM50015181(CHEMBL154302 | N-Hydroxy-4-methyl-benzamide)
Affinity DataIC50:  5.64E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC1 expressed in Sf9 insect cells using Fluor de Lys deacetylase or Fluor de Lys Green deacet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50015181(CHEMBL154302 | N-Hydroxy-4-methyl-benzamide)
Affinity DataIC50:  6.50E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed