BDBM50015401 CHEMBL1367639

SMILES Cc1ccc(cc1)-c1nn(cc1C(=O)Nc1ccc(C)c(c1)S(=O)(=O)N1CCOCC1)-c1ccccc1

InChI Key InChIKey=CZINSDVPNPAXDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015401   

TargetBile acid receptor(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50015401(CHEMBL1367639)
Affinity DataIC50:  2.62E+3nMAssay Description:Inhibition of GW4064-induced transactivation of FXR (unknown origin) expressed in HEK293T cells after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50015401(CHEMBL1367639)
Affinity DataIC50:  47nMAssay Description:Antagonist activity at human GST-tagged FXR after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed