BDBM50015857 3-Acetoxymethyl-5,5,8-trioxo-7-phenylacetoxy-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester::CHEMBL421718

SMILES CC(=O)OCC1=C(N2[C@@H]([C@@H](OC(=O)Cc3ccccc3)C2=O)S(=O)(=O)C1)C(=O)OC(C)(C)C

InChI Key InChIKey=SSACDUNHDNYWAZ-AZUAARDMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50015857   

TargetChymotrypsinogen A(Bos taurus (bovine))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015857(3-Acetoxymethyl-5,5,8-trioxo-7-phenylacetoxy-5lamb...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of alpha-chymotrypsin enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 1/2A(Sus scrofa (Pig))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015857(3-Acetoxymethyl-5,5,8-trioxo-7-phenylacetoxy-5lamb...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of Porcine pancreatic elastase (PPE) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015857(3-Acetoxymethyl-5,5,8-trioxo-7-phenylacetoxy-5lamb...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015857(3-Acetoxymethyl-5,5,8-trioxo-7-phenylacetoxy-5lamb...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed