BDBM50016675 CHEMBL55053::N-Hydroxy-N-phenethyl-4-phenyl-butyramide

SMILES ON(CCc1ccccc1)C(=O)CCCc1ccccc1

InChI Key InChIKey=SFUOMWLKDAEHOO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50016675   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016675(CHEMBL55053 | N-Hydroxy-N-phenethyl-4-phenyl-butyr...)
Affinity DataIC50:  400nMAssay Description:Invitro inhibition of rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016675(CHEMBL55053 | N-Hydroxy-N-phenethyl-4-phenyl-butyr...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016675(CHEMBL55053 | N-Hydroxy-N-phenethyl-4-phenyl-butyr...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase using guinea pig supernatantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016675(CHEMBL55053 | N-Hydroxy-N-phenethyl-4-phenyl-butyr...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed