BDBM50017857 3-(3,4-Dihydroxy-5-nitro-phenyl)-1-phenyl-propenone::CHEMBL169926

SMILES Oc1cc(\C=C\C(=O)c2ccccc2)cc(c1O)[N+]([O-])=O

InChI Key InChIKey=GOWRJXXUELPHCD-VOTSOKGWSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50017857   

TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(3-(3,4-Dihydroxy-5-nitro-phenyl)-1-phenyl-propenon...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against catechol O-methyltransferase of rat brain using 3,4-dihydroxybenzoic acid as the substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatic-L-amino-acid decarboxylase(Sus scrofa)
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(3-(3,4-Dihydroxy-5-nitro-phenyl)-1-phenyl-propenon...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against the dopamine decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(3-(3,4-Dihydroxy-5-nitro-phenyl)-1-phenyl-propenon...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against the Monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Mus musculus)
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(3-(3,4-Dihydroxy-5-nitro-phenyl)-1-phenyl-propenon...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against the Monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine 3-monooxygenase(Bos taurus)
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(3-(3,4-Dihydroxy-5-nitro-phenyl)-1-phenyl-propenon...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against the tyrosine hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Homo sapiens (Human))
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(3-(3,4-Dihydroxy-5-nitro-phenyl)-1-phenyl-propenon...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against the dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed