BDBM50019315 CHEMBL3289420
SMILES O=C(NCCN1CCCCC1)c1cccn2c1nc1cc3ccccc3cc1c2=O
InChI Key InChIKey=TXTDKLMFBBYADC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50019315
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University
Curated by ChEMBL
Johns Hopkins University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University
Curated by ChEMBL
Johns Hopkins University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair