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BDBM50019595 2-(4-Methyl-piperazin-1-yl)-1-(2-phenoxy-ethyl)-1H-benzoimidazole::CHEMBL276735

SMILES: CN1CCN(CC1)c1nc2ccccc2n1CCOc1ccccc1

InChI Key: InChIKey=DFQPTNCRXWRZKR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019595   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50019595
PNG
(2-(4-Methyl-piperazin-1-yl)-1-(2-phenoxy-ethyl)-1H...)
Show SMILES CN1CCN(CC1)c1nc2ccccc2n1CCOc1ccccc1
Show InChI InChI=1S/C20H24N4O/c1-22-11-13-23(14-12-22)20-21-18-9-5-6-10-19(18)24(20)15-16-25-17-7-3-2-4-8-17/h2-10H,11-16H2,1H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 6.90n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of histamine-induced contractions in guinea pig ileum


J Med Chem 29: 1178-83 (1987)


Article DOI: 10.1021/jm00157a010
BindingDB Entry DOI: 10.7270/Q2QR4XPC
More data for this
Ligand-Target Pair