BDBM50019906 CHEMBL3287211::US9533999, ii-11

SMILES OCc1ccc2SCC(=O)N(Cc3ccc(Cl)c(c3)C(F)(F)F)c2n1

InChI Key InChIKey=PCDAJNVDWSQAJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019906   

TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50019906(CHEMBL3287211 | US9533999, ii-11)
Affinity DataIC50:  66nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50019906(CHEMBL3287211 | US9533999, ii-11)
Affinity DataIC50:  66nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed