BDBM50020221 (-)-5-hydroxy-2-(dipropylamino)tetralin::(-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::5-hydroxy-2-(dipropylamino)tetralin::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (DP-5-ADTN)::CHEMBL273273
SMILES CCCN(CCC)C1CCc2c(O)cccc2C1
InChI Key InChIKey=MDBWEQVKJDMEMK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 26 hits for monomerid = 50020221
Affinity DataKi: 0.660nMAssay Description:In vitro binding affinity of the compound is the ability to displace [3H]-spiperone from human Dopamine receptor D3 expressed in CHO-K1 cells.More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Tested in vitro for the inhibition of [3H]-raclopride binding to Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 1.36nMAssay Description:Displacement of [3H]spiperone from rat D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.36nMAssay Description:Displacement of [3H]spiperone from cloned dopamine D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.36nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.36nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]spiperone from rat D3 dopamine receptor expressed in HEK293 cell membranes after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Tested in vitro for the inhibition of [3H]-U-86,170 binding to Dopamine receptor D3, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro binding affinity of the compound is the ability to displace [3H]-N-0437 from human Dopamine receptor D2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity against dopamine receptor D2 in rat brain tissue using [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:In vitro binding affinity of the compound is the ability to displace [3H]-spiperone from human Dopamine receptor D2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 58.8nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 58.8nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 58.8nMAssay Description:Displacement of [3H]spiperone from rat D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 153nMAssay Description:Displacement of [3H]spiperone from rat D2L dopamine receptor expressed in HEK293 cell membranes after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 344nMAssay Description:Tested in vitro for the inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor, expressed in cloned CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 466nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.04E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Activity at human dopamine D3 receptor expressed in AtT cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:50% inhibition of specific [3H]clonidine binding (0.4 nM) to Alpha-2 adrenergic receptors in rat isolated brain membranesMore data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Homo sapiens (Human))
State University Of Groningen
Curated by ChEMBL
State University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Potency to displace the specific in vitro binding of [3H]-N-0437 to calf striatal membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 10.4nMAssay Description:Activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Potency to displace the specific in vitro binding of [3H]DP-5,6-ADTN to rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 41.2nMAssay Description:Agonist activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 1.23nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]prazosin binding (0.4 nM) to rat isolated brain membr...More data for this Ligand-Target Pair