BDBM50020884 CHEMBL3287021::US9216962, CFH326-4
SMILES ONC(=O)CCCCNC(=O)c1csc(n1)-c1cscn1
InChI Key InChIKey=WZTICOBESMFADK-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50020884
Affinity DataIC50: 816nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 193nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese National Center For Drug Screening
Curated by ChEMBL
Chinese National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(epsilon-acetyl)-AMC as substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese National Center For Drug Screening
Curated by ChEMBL
Chinese National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 1.33E+3nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair