BDBM50020896 CHEMBL3287254::US9216962, CFH383
SMILES CCCCc1sc(nc1C(=O)NCCCCC(=O)NO)-c1nccs1
InChI Key InChIKey=JSLJXGGWCIEQGT-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50020896
Affinity DataIC50: 31nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 188nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese National Center For Drug Screening
Curated by ChEMBL
Chinese National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(epsilon-acetyl)-AMC as substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese National Center For Drug Screening
Curated by ChEMBL
Chinese National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 621nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair