BDBM50020896 CHEMBL3287254::US9216962, CFH383

SMILES CCCCc1sc(nc1C(=O)NCCCCC(=O)NO)-c1nccs1

InChI Key InChIKey=JSLJXGGWCIEQGT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50020896   

TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM50020896(CHEMBL3287254 | US9216962, CFH383)
Affinity DataIC50:  31nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM50020896(CHEMBL3287254 | US9216962, CFH383)
Affinity DataIC50:  188nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese National Center For Drug Screening

Curated by ChEMBL
LigandPNGBDBM50020896(CHEMBL3287254 | US9216962, CFH383)
Affinity DataIC50:  630nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(epsilon-acetyl)-AMC as substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM50020896(CHEMBL3287254 | US9216962, CFH383)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM50020896(CHEMBL3287254 | US9216962, CFH383)
Affinity DataIC50:  190nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese National Center For Drug Screening

Curated by ChEMBL
LigandPNGBDBM50020896(CHEMBL3287254 | US9216962, CFH383)
Affinity DataIC50:  621nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In DepthDetails US Patent